Non-Hodgkin's lymphoma is a cancer with lymphatic system origin. Many different types of non-Hodgkin lymphoma have been described. Non-Hodgkin lymphomas can occur at any age. The cause of non-Hodgkin's lymphoma (NHL) is still unknown.

The most common sign of Non-Hodgkin's lymphoma is a painless swelling in one or more of the lymph nodes of the neck, collarbone region, armpits, or groin. More general symptoms may include: fever, weight loss, loss of appetite, fatigue and severely itchy skin.

The only way to get a definite diagnosis is to make a biopsy of the suspicious lymph node. Lymph node is removed (it is a minor surgery) and after that examined under a microscope. X-ray or CT scan of the body may detect the presence and size of tumor. PET-CT scanning is also useful to detect non-Hodgkin's lymphomas. According to a number of affected lymph nodes and their spread, doctor stages the disease. The earlier the diagnosis is made, the greater the chance for a successful treatment.

Factors that affect the preferred choice of treatment include: lymphoma type and stage, patient’s age and general health. Treatment plans for children vary according to their age, physical development, and sexual maturity of the individual child.

Over 75% of newly diagnosed patients are cured by the latest methods of chemotherapy and radiation therapy, and the survival statistics for Non-Hodgkin's lymphoma patients have improved greatly.

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